Subject(s)
Adrenergic beta-Antagonists/administration & dosage , Antihypertensive Agents/administration & dosage , Atenolol/administration & dosage , Benzopyrans/administration & dosage , Clinical Trials as Topic , Double-Blind Method , Ethanolamines/administration & dosage , Humans , Hypertension/drug therapy , Metoprolol/administration & dosage , Prospective Studies , Time Factors , Vasodilator Agents/administration & dosageABSTRACT
Fifty cases with pyogenic meningitis, aged 15 to 72 years, with a male:female ratio of 5:1, were studied. The majority of cases (70%) were in the 15 to 25 years age group. The organisms detected in the 29 culture-positive cases included S aureus (12), pneumococci (9) and meningococci (8). Thirteen patients died; the poor prognostic factors included old age, the presence of coma or shock, CSF sugar below 10 mg/dl or protein above 750 mg/dl and the presence of gram negative organisms in the CSF.
Subject(s)
Adolescent , Adult , Age Factors , Aged , Female , Humans , India , Male , Meningitis/blood , Meningitis, Meningococcal/blood , Meningitis, Pneumococcal/blood , Middle Aged , Staphylococcal Infections/bloodABSTRACT
Ninety patients with aluminum phosphide poisoning have been studied over a period of 3 years. Epigastric pain and vomiting were the common initial clinical features, followed 12 to 24 hours later by cardiogenic shock, oliguria, altered mental state and respiratory distress. Death occurred within 24 to 72 hours presumably due to poison-induced toxic chemical myocarditis as reflected by electrocardiographic changes. The overall mortality was 63.3%. Intravenous magnesium sulphate, probably due to its membrane stabilizing action, appears to be related to the reduction in mortality from 90% to 52% in the latter 62 cases.